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Develop engaged and talented individuals to achieve their career aspirations.Experience HighlightsProven track record of project delivery at a Large Pharma company in all phases of development with a demonstration of strategic thinking, innovation, operational excellence and strong resource management.Leadership of a large organization and recognized for change agility and ability to develop talent through organizational construct modification. Capability in addressing consumers needs through proven business acumen.Demonstrated leadership in matrix team setting. Led the Chantix Pharmaceutical Sciences Team (1997-2006) and Pharmaceutical Sciences Alliance Manager for a large Pharma collaboration with Merck on ertugliflozin (2012-present).Strong interpersonal skills in cross-functional and multi-disciplinary setting. Member of the Impurity Council which includes Pharmaceutical Sciences, Drug Safety R&D and Pharmacokinetics, Dynamics and Metabolism to review projects and provide guidance around impurity control and qualification. (2003-2016).Proven track record of participating in the planning and implementation of new initiatives. Designed, implemented and managed a new process for Synthesis Management Team in Medicianl Design (2017-present)International scientific track record as shown by Membership of the Inorganic & Organic Chemistry Grant Selection Committee, NSERC. Canada, 2003-2006; Organic Process Research and Development Editorial advisory board, (2007-present); chairing symposia (The Role of Organic Synthesis in Early Clinical Drug Development II, Symposium, 2003 and The Science and Strategy of Process Chemistry: From Molecules to Pharmaceutical Drugs, 2010) and the Asymchem Scientific Advisory Board (2013-present). Served on the Editor Search Committee on one of the most prestigious journal of the American Chemical Society (2016). EducationPh.D., December 1995, University of California at Berkeley. Title of Thesis: "The Synthesis of the Core of the Zaragozic Acids and Squalestatins." Research Advisor: Clayton H. HeathcockM.Sc., March 1991, Universit Laval, Qu閎ec, Canada. Title of Thesis: "Synth鑣e totale de la (dl)-12-hydroxyabi閠a-8,11,13-triene-3,7-dione et approche la synth鑣e de la Candelabrone." Research Advisor: Robert H. BurnellB.Sc., May 1989, Universit Laval, Qu閎ec, Canada.Professional ExperiencePfizer Inc., Pharmaceutical Sciences, Chemical R&D (Aug. 1995-present)Chemical R&DExecutive Director, Jan. 2014-present; Senior Director, Apr. 2010-Dec. 2013; Director, Mar. 2005-Apr. 2010; Associate Director, Nov. 2003-Mar. 2005; Manager, Mar. 2002-Nov. 2003; Project Leader, Aug. 2000-Mar. 2002; Senior Research Scientist, Feb. 1998-Aug. 2000; Research Scientist, Aug. 1995-Feb. 1998.Genentech, Medicinal Chemistry (Apr. 1991-Aug. 1991)Medicinal Chemistry InternResearch and Managerial ExperienceExecutive Director, Chemical Research & Development. (2014-present) - Managed ~60 member chemistry organization supporting the portfolio covering projects from pre-clinical to commercial launch. Supported several managers on strategy for project progression, workforce planning, colleague development and budget. Partnered with Global External Supply group on vendor selection and interactions. Worked in partnership with Worldwide Medicinal Chemistry to support the early development portfolio and with Pfizer Global Supplies for assets approaching commercialization. Senior Director, Chemical Research & Development. (2010-2013) Managed both scientific staff and managers in the late stage development group of CRD. Key point of contact in Co-Development in the introduction of new product to Pfizer Global Supply. Led the effort on outsourcing on development activities within CRD. Participated in several due diligence evaluations as part of business development. Worked in collaboration with partner lines to assess the regulatory application of quality by design (QbD) principles and the interpretation of new guidelines on control of genotoxic impurities. Key member of the Lab of the Future team which led to a major capital project in Pharmaceutical Sciences. Director, Chemical Research & Development. (2005-2010) Transition to the late development group and managed a group of ~20 chemists. Involved in project assessment and transfers following the Pharmacia and Wyeth acquisitions. Led the recruiting team for CRD to talent acquisition. Co-Led the creation of the CRD workflows to standardize project team deliverables and expectations based on project progression. Created the CRD resource prediction template to access overall resource needs and budget for a closed loop resource management system. Led a multi-disciplinary team on developing contemporary practices meeting regulatory expectations for API stability package for new product registration. Project Leader, Process Research. (2000-2002), Manager, Chemical Research & Development. (2002-2003) & Associate Director, Chemical Research & Development.(2003-2005) Increased managerial responsibilities and focus exclusive to early development. Developed the strategy for a much larger portfolio of assets and represented CRD on the Early Development Portfolio Management Team. Started involvement with outsourcing and vendor interactions to mitigate resource constraints. Participated in a number of initiatives to expedite speed of early candidates within Pharmaceutical Sciences. Involved in the organizational design of the department following a merger and the recruitment of employees from research sites that were getting closed. Managed the contracts of the consultants hired by our department. Senior Research Scientist. Process Research (1998-2000) - February 1998-August 2000: Point of contact to the Central Nervous System discovery team (Groton CT) and Pain team (Nagoya, Japan) for introduction on new drug candidates into development. Collaborated with Legal group on patent strategy for new CNS and Pain drug candidates. Supervised two direct reports and enabled chemistry for First in Human studies. Research Scientist. Process Research. (1995-1998) - August 1995-February 1998: supervised one direct report and defined the synthetic strategy of mid-stage drug candidates. Worked in the laboratory and developed technical transfer documentation for scale-up of the chemistry selected. Led the department recruiting effort. AwardsDare to Try Award; Ertugliflozin co-crystal (one of five teams selected across Pfizer in 2016)Pharmaceutical Sciences Pharmatherapeutics Team of the year; ertugliflozin (2014)Pfizer Groton Site Team of the Year Award for Lab of the Future (2010)Top 300 Pfizer Managers based on top 75th percentile in Gallup 12 results (2010)Leader the outstanding Early Clinical Management Team of the year; nicotine partial agonist, (2000). Also received Groton/New London teamwork award (2004) and PGRD team award (2006).Pfizer Fellowship, Department of Chemistry, University of California at Berkeley, (August 1994-July 1995).Fonds FCAR Fellowship, Department of Chemistry, University of California at Berkeley, (August 1991-July 1994).Fonds FCAR Fellowship, Department of Chemistry, Universit Laval, Qu閎ec, (May 1989-January 1991). Appendix: Presentations, Publications and PatentsPresentations:Burnell, R. H., Caron, S. and Girard, M. "Approche de la synth鑣e de la candelabrone." Presented at the 58th ACFAS meeting, Qu閎ec City, Qu閎ec, Canada. May 1990.Caron, S. and Burnell, R. H. "Approche la synth鑣e de la candelabrone." Presented at the 59th ACFAS meeting, Sherbrooke, Qu閎ec, Canada. May 1991.Caron, S. and Heathcock, C. H. "Approach Towards the Synthesis of the core of the Zaragozic acids." Presented at the 208th National Meeting of the ACS, Washington, D.C., August 1994.Caron, S.; Stoermer, D.; Heathcock, C. H. "The Total Synthesis of Zaragozic Acid A/Squalestatin S1." Presented at the Gordon Research Conference on Stereochemistry, Newport, R.I., June 1996.Caron, S. "Directed Ortho Metalation of Neopentyl Benzoates and its Application in the Synthesis of CP-195,543." Presented at the Universit de Montr閍l, Quebec, Canada, May 1998.Caron, S. "L抩rtho-lithiation des benzoates de n閛pentyl et son application dans la synth鑣e du CP-195,543." Presented at the 66th ACFAS meeting, Qu閎ec City, Qu閎ec, Canada. May 1998.Caron, S. "Directed Ortho Metalation of Neopentyl Benzoates and its Application in the Synthesis of CP-195,543." Presented at the NSF Workshop on Organic Synthesis and Natural Products Chemistry, Ashland, New Hampshire, July 1998.Caron, S. 揟he Synthesis of CP-195,543. Presented at Cornell University, Ithica, April 1999.Caron, S. 揟he Synthesis of CP-195,543. Presented at the 2nd International Conference on Process Research and Development, New Orleans, April 1999.Caron, S.  Process Research Towards an Efficient Synthesis of a PDE4/TNFa Inhibitor. Presented at the University of California at Berkeley, September 1999.Caron, S.  Process Research Towards an Efficient Synthesis of a PDE4/TNFa Inhibitor. Presented at Organic Reactions and Processes Gordon Research Conference, Bristol RI, July 2000.Caron, S.  Process Research Towards an Efficient Synthesis of NK1 Receptor Antagonist. Presented at 84th CSC meeting, Montreal, May 2001.Caron, S. 揚rocess Research Towards an Efficient Synthesis of a NK1 Receptor Antagonist. Presented at Heterocycles Gordon Research Conference, Newport RI, July 2001.Caron, S. 揚rocess Research Towards an Efficient Synthesis of a NK1 Receptor Antagonist and a COX-2 Inhibitor. Presented at the IBC and Sepracor抯 Third International Symposium on New Synthetic Methods; Chemistry Advancements for Effective Drug Development, Naples, FL, March 2001.Caron, S. 揇iscovery and Development of Novel Catalysts. 1) Process Research Towards an Enantioselective Synthesis of an NK-1 Antagonist. 2) A New Class of Ligands for the Palladium-Catalyzed Aryl Amination. Presented at the Universit of Montr閍l, Qu閎ec, Canada, November 2002.Caron, S. 揑ntroductory Remarks: The Role of Organic Synthesis in Early Clinical Drug Development. 226th ACS National Meeting, New York, September 2003.Caron, S. 揂cademic Industrial Relations, A Changing Landscape. The International conference for New Directions in Chemical Synthesis. Presented at Edinburgh, Scotland, July 2004.Caron, S. 揚rocess Research and Development Towards a Selective and Partial GABAA Receptor Inverse Agonist. Presented at the University of Ottawa, Canada, March 2005.Caron, S. 揤arenicline tartrate: A chemical journey. Presented at the 231st ACS National Meeting, Atlanta, March 2006.Caron, S. 揟he Discovery and Process Development of Varenicline Tartrate: A New Treatment in Smoking Cessation. Presented at the Synthetic Heterocyclic Chemistry Conference (Scientific Update), Barcelona, Spain, April 2007.Caron, S. 揚rocess Research and Development of a Factor Xa Inhibitor. Presented at the Stereochemistry Gordon Research Conference, Newport, RI, July 2008.Caron, S. 揝trategies in Pharmaceutical Development. Presented at the 2010 NSF Workshop on Organic Synthesis and Natural Products Chemistry, Holderness, NH, July 2010.Caron, S. 揚rocess Research and Development of Tofacitinib Citrate. Presented at the 3rd Asymchem Pharmaceutical CMC Symposium, Tianjin China, September 2012.Caron, S. 揚rocess Research and Development of Tofacitinib Citrate and Applications of Base Metal Catalysis Presented at the University of California at Los Angeles, February 2013.Caron, S. 揇eveloping an API Commercial Synthesis; Expectations and Recent Examples Presented at the University of California at San Diego, November 2014.Caron S. 揈rtugliflozin API Development Presented at Merck, Rahway, October 2015.Caron, S. 揇eveloping an API Commercial Synthesis; Expectations and Recent Examples Presented at the University of Rhode Island, October 2015.Caron, S. 揜elevance of Green Chemistry in Synthetic Methodology and Process Development Presented at the School of Pharmaceutical Science and燭echnology Asymchem Green Chemistry Symposium, China, October 2016.Caron, S. 揜elevance of Green Chemistry in Synthetic Methodology and Process Development Presented at the School of Pharmaceutical Science and燭echnology Tianjin University, China, October 2016.Publications:Burnell, R. H.; Caron, S. "Synthesis of Aromatic Diterpenes; Synthesis of 12hydroxyabieta-8,11,13-trien-3,7-dione." Synth. Commun., 1991, 21, 127.Burnell, R. H.; Caron, S. "Approach to the synthesis of candelabrone and synthesis of 3,7-diketo-12-hydroxyabieta-8,11,13-triene." Can. J. Chem. 1992, 70, 1446.Caron, S.; Desfoss閟, S.; Dionne, R.; Th閎erge, N.; Burnell, R. H. "Synthesis of Some Minor Quinoline Alkaloids Found in Galipea Longiflora." J. Nat. Prod. 1993, 56, 138.Caron, S.; McDonald, A. I.; Heathcock, C. H. "Synthesis of 1-Substituted and 1,4Disubstituted 2,3-Di-O-benzyl-1,6-anhydrogalactofuranoses." J. Org. Chem., 1995, 60, 2780.Caron, S.; McDonald, A. I.; Heathcock, C. H. "An Improved Synthesis of 1,6-Anhydro-2,3-di-O-benzyl-b-D0xylo-hexopyranos-4-ulose." Carb. Res., 1996, 281, 179.Stoermer, D.; Caron, S.; Heathcock, C. H. "Total Synthesis of Zaragozic Acid A (Squalestatin S1). Degradation to a Relay Compound and Reassembly of the Natural Product." J. Org. Chem., 1996, 61, 9115.Caron, S.; Stoermer, D.; Mapp, A. K.; Heathcock, C. H. "Total Synthesis of Zaragozic Acid A (Squalestatin S1). Synthesis of the Relay Compound." J. Org. Chem., 1996, 61, 9126.Caron, S.; Hawkins, J. M. "Directed Ortho Metalation of Neopentyl Benzoates with LDA: Preparation of Arylboronic Acids." J. Org. Chem., 1998, 63, 2054.Caron, S.; Vazquez, E. 揂 Versatile and Efficient Synthesis of Substituted 1H-Indazoles. Synthesis, 1999, 588.Caron, S. 揟he Synthesis of CP-195,543, an LTB4 Antagonist for the Treatment of Inflammatory Diseases. Curr. Opin. Drug Discovery Dev., 1999, 2, 550.Caron, S.; Vazquez, E.; Wojcik, J. M. 揚reparation of Tertiary Benzylic Nitriles from Aryl Fluorides. J. Am. Chem. Soc., 2000, 122, 712.Caron, S.; Do, N. M.; Sieser, J. E. 揂 Practical, Efficient, and Rapid Method for the Oxidation of Electron Deficient Pyridines Using Trifluoroacetic Anhydride and Hydrogen Peroxide-Urea Complex. Tetrahedron Lett., 2000, 41, 2299.Caron, S.; Massett, S. S.; Bogle, D. E.; Castaldi, M. J.; Braish, T. F. 揂n Efficient and Cost-Effective Synthesis of 2-Phenyl-3-aminopyridine. Org. Process Res. Dev., 2001, 5, 254.Caron, S.; Vazquez, E. 揟he Synthesis of a Selective PDE4/TNFa Inhibitor. Org. Process Res. Dev., 2001, 5, 587. Caron, S.; Wojcik, J. M.; Vazquez, E.  Nucleophilic Aromatic Substitution of Aryl Fluorides by Secondary Nitriles: Preparation of 2-(2-Methoxyphenyl)-2-methylpropionitirle. Org. Syn. 2002, 79, 209. Ghosh, A.; Sieser, J. E.; Caron, S.; Watson, T. J. N. 揝ynthesis of the kappa-agonist CJ-15,161 via a palladium-catalyzed cross-coupling reaction. Chem. Commun. 2002, 1644.Caron, S.; VazquezHYPERLINK "http://pubs.acs.org/cgi-bin/article.cgi/joceah/2003/68/i10/html/" \l "jo034274rAF2", E.; Stevens, R. W.; Nakao, K.; Koike, H.; Murata Y. 揈fficient Synthesis of [6-Chloro-2-(4-chlorobenzoyl)-1H-indol-3-yl]-acetic Acid, a Novel COX-2 Inhibitor. J. Org. Chem. 2003, 68, 4104.Caron, S.; Do, N. M.; Arpin, P.; Lariv閑, A. 揈nantioselective Addition of a Trifluoromethyl Anion to Aryl Ketones and Aldehydes. Synthesis, 2003, 1693.Singer, R. A.; Caron, S.; McDermott, R. E.; Arpin, P.; Do, N. M. 揂lternative Biarlyphosphines for Use in the Palladium-Catalyzed Amination of Aryl Halides. Synthesis, 2003, 1727.Caron, S.; Do, N. M. 揋eneration of Bromophenyllithium Reagents from Dibromobenzenes and Addition to Carbonyl and Nitrile electrophiles. Synlett, 2004, 1440.Brooks, P. R.; Caron, S.; Coe, j. W.; Ng, K. K.; singer, R. A.; Vazquez, E.; Vetelino, M. G.; Watson, Jr., H. H.; Whritenour, D. C.; Wirtz, M. C. 揝ynthesis of 2,3,4,5-Tetrahydro-1,5-methano-1H-3-benzazepine via Oxidative Cleavage and Reductive Amination Strategies. Synthesis, 2004, 1755.Ghosh, Arun; Sieser, Janice E.; Caron, Stephane; Couturier, Michel; Dupont-Gaudet, Kristina; Girardin, Melina. 揅u-Catalyzed N-Arylation of Oxazolidinones: An Efficient Synthesis of the d?Opioid Receptor Agonist CJ-15161. J. Org. Chem. 2006, 71, 1258. Caron, Stphane; Do Nga M.; McDermott,Ruth E.; S. Bahmanyar  Regioselective Synthesis of an Imidazo[4,5-c]pyridine through Selective Acylation of 3,4-Diaminopyridine: Synthesis of CP-885,316. Org. Process Res. Dev. 2006, 10, 257. Dobo, Krista L.; Greene, Nigel; Cyr, Michelle O.; Caron, St閜hane; Ku, Warren W. 揟he application of structure-based assessment to support safety and chemistry diligence to manage genotoxic impurities in active pharmaceutical ingredients during drug development. Regulatory Toxicology and Pharmacology, 2006, 44, 282.Caron, Stephane; Dugger, Robert W.; Ruggeri, Sally Gut; Ragan, John A.; Ripin, David H. Brown. 揕arge-Scale Oxidations in the Pharmaceutical Industry. Chem. Rev. 2006, 106, 2943.Andresen, Brian M.; Caron, St閜hane; Couturier, Michel; DeVries, Keith M.; Do, Nga M.; Dupont-Gaudet, Kristina; Ghosh, Arun; Girardin, Melina; Hawkins, Joel M.; Makowski, Teresa M.; Riou, Maxime; Sieser, Janice E.; Tucker, John L.; Vanderplas, Brian C.; Watson, Timothy J. N. 揚rocess research and scale-up of the k?opioid receptor agonist CJ-15,161 drug candidate. Chimia, 2006, 60, 554.Caron, Stphane; Do, Nga M.; Sieser, Janice E.; Arpin, Patrice; Vazquez, Enrique. Process Research and Development of an NK-1 Receptor Antagonist.  Enantioselective Trifluoromethyl Addition to a Ketone in the Preparation of a Chiral Isochroman. Org. Process Res. Dev. 2007, 11, 1015-1024.Brandt, Thomas A.; Caron, St閜hane; Damon, David B.; DiBrino,Joseph; Ghosh, Arun; Griffith, David A.; Kedia, Sandeep; Ragan, John A.; Rose, Peter R.; Vanderplas, Brian C.; Wei, Lulin. HYPERLINK "http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6THR-4TS6SGY-D&_user=5844500&_coverDate=10%2F25%2F2008&_alid=853861992&_rdoc=1&_fmt=high&_orig=search&_cdi=5289&_sort=d&_docanchor=&view=c&_ct=10&_acct=C000000313&_version=1&_urlVersion=0&_userid=5844500&md5=ed6ffc8e92bd64b214363e6f4063f6d6"Development of two synthetic routes to CE-178,253, a CB1 antagonist for the treatment of obesity. Tetrahedron, 2009, 65, 3292.Caron, St閜hane; Do, Nga M.; Sieser, Janice E.; Whritenour, David C.; Hill, Paul D. 揚reparation of a Corticotropin-Releasing Factor Antagonist by Nucleophilic Aromatic Substitution and Copper-Mediated Ether Formation. Org. Process Res. Dev. 2009, 13, 324.CaronHYPERLINK "http://pubs.acs.org/doi/full/10.1021/jo902159z" \l "cor1", St閜hane; Wei, Lulin;燚ouville, Jasmin; Ghosh, Arun.爴Preparation and Utility of Trihaloethyl Imidates: Useful Reagents for the Synthesis of Amidines J. Org. Chem., 2010, 75, 945?47.Lafrance, Danny G.; Caron, St閜hane. 揘ew Synthetic Route to PF-734200. Org. Process Res. Dev. 2012, 16, 409-414.Brenek, Steven; Caron, St閜hane; Chisowa, Esmort; Colon-Cruz, Roberto; Delude,Mark P.; Drexler, Michele T.; Handfield, Robert E.; Jones, Brian P.; Nadkarni, Durgesh; Nelson, Jade D.; Olivier, Mark; Weekly, R. Matt; Bellinger, G. C. A.; Brkic, Zinka; Choi, Neil; Desneves, Joe; Lee, Maria A.-P.; Pearce, Wayne; Watson, Jessica K.. HYPERLINK "http://pubs.acs.org/doi/abs/10.1021/op300130p"Development of a Second-Generation Process to Antibacterial Candidate Sulopenem. Org. Process Res. Dev. 2012, 16, 1338-1347..Brenek, Steven; Caron, St閜hane; Chisowa, Esmort; Delude, Mark P.; Drexler, Michele T.; Handfield, Robert E.; Ide, Nathan D.; Nadkarni, Durgesh; Nelson, Jade D.; Olivier, Mark; Perfect, Hahdi; Phillips, James E.; Teixeira, John J. R.; Weekly, R. Matt; Zelina, John P. HYPERLINK "http://pubs.acs.org/doi/abs/10.1021/op300131e"Development of a Practical and Convergent Process for the Preparation of Sulopenem. Org. Process Res. Dev. 2012, 16, 1348-1359.Caron, St閜hane; Jones, Brian P.; Wei, Lulin. 揚reparation of Substituted-Benzimidazoles and Imidazopyridines Using 2,2,2-Trichloroethyl Imidates. Synthesis, 2012, 44, 3049-3054.Caron, St閜hane; Jones, Brian P.; Wei, Lulin.  HYPERLINK "javascript:goFormView(%22/OrgSyn/orgsyn/orgsyn_form.asp?formgroup=quick_form_group&dbname=orgsyn&formmode=edit&unique_id=undefined&commit_type=undefined%22,%2217%22)" Preparation of N1-Phenylacetamidine 4-Bromobenzoate Using 2,2,2-Trichloroethyl Acetimidate Hydrochloride.敔Org. Syn.. 2013, 90, 174-181.Bowles, Paul; Brenek, Steven J.; Caron, St閜hane; Do, Nga M.; Drexler, Michele T.; Duan, Shengquan; Dube, Pascal; Hansen, Eric C.; Jones, Brian P.; Jones, Kris N.; et al;  HYPERLINK "https://scifinder.cas.org/scifinder/references/answers/D4FC6602X86F350ACX1EB2234131CE9C7DF7:D4FCF6EDX86F350ACX25691B7A1765EC6331/1.html?nav=eNpdkM8vA0EUx59tRIQDLiJCHByEZFZVt6QSqj9obLbSIuIio53UsruznZlWexEOOLg4KBcHBzfuxJ8gcRQuEnHnKnEy2xJhTi_v-51Pvu979QaNAhqwgP7YaCKa0OKx5TEtEQgOR6LLI0Ft3D8divhDWjAe1QIBv7SucQbtG7iEkYWdPEo6guQJ63g9v_jYPRhToCEJjSVsFUmZQduvzyjaa4TtX1V7Wo5fDhWAsgsAPglcF9AdWVyYTaVXk8ZS3FiQg5FanUmnFueTxoyAZtN2KROSwAuwDT75D-R203bTpPBvqzD6N980pRbBzn0f23k4-3yX-VZ-8rmen3PpH6Isj7KYI8qzmCFOWIkwlKM2Nh2UpbZNHZSRETIuyU4cXZ73nL7cKaDo0GpXUixnOtiaIxUBA7oEqRKk1kBqHaTWQWodpEpnWIcmu-IRuYAu3UurFoVpqbrpbJLcLObrGSLCZdeV4Tprx3gy-iM_WY8r1efBXq_Ln5Nrrm_9NrZXPbm5HvV5XW-1ynraJqeg9spfuEejiA&key=caplus_2013:1974382&title=Q29tbWVyY2lhbCBSb3V0ZSBSZXNlYXJjaCBhbmQgRGV2ZWxvcG1lbnQgZm9yIFNHTFQyIEluaGliaXRvciBDYW5kaWRhdGUgRXJ0dWdsaWZsb3ppbg&launchSrc=reflist&pageNum=1&sortKey=ACCESSION_NUMBER&sortOrder=DESCENDING" Commercial Route Research and Development for SGLT2 Inhibitor Candidate Ertugliflozin Org. Process Res, Dev.?014,?8,?6-81.Caron, St閜hane; Thomson, Nicholas  HYPERLINK "http://pubs.acs.org.proxy1.athensams.net/doi/abs/10.1021/jo502879m" Pharmaceutical Process Chemistry: Evolution of a Contemporary Data-Rich Laboratory Environment. J. Org. Chem. 2015, 80, 2943-2958.Hansen, Eric; Pedro, Dylan; Wotal, Alexander; Gower, Nicholas; Nelson, Jade; Caron, St閜hane; Weix, Daniel "New Ligands for Nickel Catalysis from Diverse Pharmaceutical Heterocycle Libraries" Nature Chem., 2016, 8, 1126-1130.Wang, Ke; Liu, Fangfang; Caron, St閜hane Caron; Vukovinsky Kimberly E. 揇istribution Quantification of Synthetic Amino Acid Oligomers Pharm. Eng. 2016, 36(6), 81-85.Book or Book Chapter:"Fundamentals of Early Clinical Drug Development; From Synthesis Design to Formulation." Ahmed F. Abdel-Magid & St閜hane Caron, Editors. Wiley-Interscience, 2006.揜esponsibilities of the Process Chemist: Beyond Synthetic Organic Chemistry. Chapter #7 in "Fundamentals of Early Clinical Drug Development; From Synthesis Design to Formulation." Ahmed F. Abdel-Magid & St閜hane Caron, Editors. Wiley-Interscience, 2006.揚ractical Synthetic Organic Chemistry: Reactions, Principles, and Techniques. St閜hane Caron Editor. Wiley, 2011.揘ucleophilic Aromatic Substitution. Chapter #4 with Arun Ghosh in 揚ractical Synthetic Organic Chemistry: Reactions, Principles, and Techniques. St閜hane Caron Editor. Wiley, 2011.揈lectrophilic Aromatic Substitution. Chapter #5 with in 揚ractical Synthetic Organic Chemistry: Reactions, Principles, and Techniques. St閜hane Caron Editor. Wiley, 2011.揝elected Metal-Mediated Cross-Coupling Reactions. Chapter #6 with Arun Ghosh, Sally Gut Ruggeri, Nathan D. Ide, Jade D. Nelson and John A. Ragan in 揚ractical Synthetic Organic Chemistry: Reactions, Principles, and Techniques. St閜hane Caron Editor. Wiley, 2011.揜eductions. Chapter #8 with Sally Gut Ruggeri, Pascal Dub? Nathan D. Ide, Kristin E. Price, John A. Ragan and Shu Yu in 揚ractical Synthetic Organic Chemistry: Reactions, Principles, and Techniques. St閜hane Caron Editor. Wiley, 2011.揝ynthesis of Common Aromatic Heterocycles. Chapter #13 in Practical Synthetic Organic Chemistry: Reactions, Principles, and Techniques. St閜hane Caron Editor. Wiley, 2011.揝ynthetic Route Development of Selected Contemporary Pharmaceutical Drugs. Chapter #15 in Practical Synthetic Organic Chemistry: Reactions, Principles, and Techniques. St閜hane Caron Editor. Wiley, 2011.揋eneral Solvent Properties. Chapter #19 in Practical Synthetic Organic Chemistry: Reactions, Principles, and Techniques. St閜hane Caron Editor. Wiley, 2011.Granted Patents:揗ethods of Preparing 4-Cyano-4-(Substituted Indazole) Cyclohexane Carboxylic Acids Useful as PDE4 Inhibitors. Caron, S.; U. S. 6005118, 12/21/1999.揚rocesses and Intermediates for Preparing Substituted Indazole Derivatives. Caron, S.; Eisenbeis, S. A. U. S. 6011159, 1/4/2000. 揚rocesses for preparing substituted chromanol derivatives. Piscopio, A.; Hawkins, J. M.; Caron, S.; Kelly, S. E.; Raggon, J. W.; Castaldi, M. J.; Dugger, R. W.; Ruggeri, S. G.; U. S. 6096906, 8/1/2000.揚rocesses and intermediates for preparing substituted chromanol derivatives. Piscopio, A.; Hawkins, J. M.; Caron, S.; Kelly, S. E.; Raggon, J. W.; Castaldi, M. J.; Dugger, R. W.; Ruggeri, S. G.; U.S. 6288242, 9/11/2001.揚rocess for preparing benzylnitriles. Caron, S.; U.S. 6303782, 10/16/2001.揚rocess for preparing 2-phenyl-3-aminopyridine, substituted phenyl derivatives, thereof, and salt thereof. Caron, S.; U.S. 6316632, 11/13/2001. 揚rocesses and intermediates for preparing substituted chromanol derivatives. Piscopio, A.; Hawkins, J. M.; Caron, S.; Kelly, S. E.; Raggon, J. W.; Castaldi, M. J.; Dugger, R. W.; Ruggeri, S. G.; U.S. 6355825, 3/12/2002. 揚rocesses and intermediates for preparing substituted chromanol derivatives. Piscopio, A.; Hawkins, J. M.; Caron, S.; Kelly, S. E.; Raggon, J. W.; Castaldi, M. J.; Dugger, R. W.; Ruggeri, S. 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W.; Kawamura, K.; Uchida, C.; Koike, H.; Caron, S.; U.S. 6608070, 8/19/2003.揙ptically active 3-[(2-Piperazinylphenyl)methyl]-1-[4-(trifluoromethyl)phenyl]-2-pyrrolidinone compounds as 5-HT 1D receptor selective antagonists. Howard, H. R. Jr; Adam, M.; Caron, S.; EP 1113015, 9/15/2004.揚rocesses for preparing substituted aryl boronic acids  HYPERLINK "http://www.micropat.com/perl/di/psrecord.pl?ticket=302269348856&listid=84128200606011547&container_id=323345&patnum=US7045652B2" \l "hit3#hit3" Caron, S.; Nowakowski, J.; U.S. 7045652, 5/16/2006.揚rocess for preparing haloalkyl pyrimidines Singer, R. A.; McDermott, R. E ; Do, N. M.; Caron, S.; EP1549649 B1, 7/26/2006.揗ethods for preparing N-arylated oxazolidinones via a copper catalyzed cross coupling reaction Ghosh, A.; Caron, S.; Sieser, J. E.; U.S. 7223870, 5/29/2007."Benzyl(idene)-lactam derivatives Tao, Y.; Raggon, J. W.; Do, N. M.; Brodney, M. A.; Helal, C. J.; Caron, S.; U.S. 7479449, 1/20/2009. 揗ethods for preparing SGLT2 inhibitors Brenek, S. J.; Caron, S.; Nelson, J. D. HYPERLINK "https://patents.justia.com/inventor/jade-d-nelson" ; Webster, M. E.; Weekly, R. 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